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MLB Pitcher Strikeout Props — Tuesday, April 21, 2026

Top projected strikeout arms today: Sean Burke (7.4 K), Luis Castillo (7.1 K), Kyle Harrison (6.8 K). Projected strikeouts for every probable starter, adjusted for opponent K-rate and ballpark. 15 games on the slate.

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Astros @ GuardiansProgressive Field · 6:10 PM ET
Ryan Weiss
Outside tracked rotation
proj K
@
Parker Messick
Outside tracked rotation
proj K
Reds @ RaysTropicana Field · 6:40 PM ET
Chase Burns
Outside tracked rotation
proj K
@
Steven Matz
Outside tracked rotation
proj K
Cardinals @ MarlinsloanDepot park · 6:40 PM ET
RHP · 8.3 K/9 · 106 Stuff+
5.6
proj K vs Marlins
Favorable K matchup
@
RHP · 8.8 K/9 · 104 Stuff+
5.0
proj K vs Cardinals
Tough K matchup
Brewers @ TigersComerica Park · 6:40 PM ET
LHP · 10.2 K/9 · 108 Stuff+
6.8
proj K vs Tigers
Neutral matchup
@
Keider Montero
Outside tracked rotation
proj K
Braves @ NationalsNationals Park · 6:45 PM ET
RHP · 10 K/9 · 110 Stuff+
6.6
proj K vs Nationals
Neutral matchup
@
Foster Griffin
Outside tracked rotation
proj K
Yankees @ SoxFenway Park · 6:45 PM ET
RHP · 10.2 K/9 · 108 Stuff+
6.1
proj K vs Sox
Neutral matchup
@
LHP · 8.6 K/9 · 102 Stuff+
4.9
proj K vs Yankees
Tough K matchup
Twins @ MetsCiti Field · 7:10 PM ET
RHP · 9.2 K/9 · 106 Stuff+
5.6
proj K vs Mets
Neutral matchup
@
Nolan McLean
Outside tracked rotation
proj K
Orioles @ RoyalsKauffman Stadium · 7:40 PM ET
RHP · 7.7 K/9 · 114 Stuff+
4.9
proj K vs Royals
Tough K matchup
@
Kris Bubic
Outside tracked rotation
proj K
Phillies @ CubsWrigley Field · 7:40 PM ET
LHP · 10.2 K/9 · 110 Stuff+
6.4
proj K vs Cubs
Neutral matchup
@
Shota Imanaga
Outside tracked rotation
proj K
Pirates @ RangersGlobe Life Field · 8:05 PM ET
Carmen Mlodzinski
Outside tracked rotation
proj K
@
RHP · 9 K/9 · 108 Stuff+
5.7
proj K vs Pirates
Neutral matchup
Padres @ RockiesCoors Field · 8:40 PM ET
RHP · 6.8 K/9 · 101 Stuff+
3.9
proj K vs Rockies
Favorable K matchup
@
Jimmy Herget
Outside tracked rotation
proj K
Jays @ AngelsAngel Stadium · 9:38 PM ET
Patrick Corbin
Outside tracked rotation
proj K
@
Jack Kochanowicz
Outside tracked rotation
proj K
Athletics @ MarinersT-Mobile Park · 9:40 PM ET
Jacob Lopez
Outside tracked rotation
proj K
@
RHP · 9.2 K/9 · 113 Stuff+
7.1
proj K vs Athletics
Favorable K matchup
Sox @ DiamondbacksChase Field · 9:40 PM ET
RHP · 9 K/9 · 98 Stuff+
7.4
proj K vs Diamondbacks
Neutral matchup
@
RHP · 8 K/9 · 104 Stuff+
6.3
proj K vs Sox
Favorable K matchup
Dodgers @ GiantsOracle Park · 9:45 PM ET
RHP · 8.4 K/9 · 128 Stuff+
6.3
proj K vs Giants
Neutral matchup
@
Landen Roupp
Outside tracked rotation
proj K

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Proj K reflects each pitcher's baseline rate adjusted for the opposing lineup's strikeout rate vs. that hand (L3) and the ballpark's strikeout environment (L4). Game-day weather (L2) is applied in the live engine. For entertainment purposes only.

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