MLB Pitcher Strikeout Props — Sunday, September 21, 2025
Top projected strikeout arms on Sunday, September 21, 2025: Spencer Strider (8.7 K), Sean Manaea (6.6 K), Sean Burke (6.4 K). Projected strikeouts for every probable starter, adjusted for opponent K-rate and ballpark. 15 games on the slate.
Projected starters
Braves @ TigersComerica Park · 1:10 PM ET
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Athletics @ PiratesPNC Park · 1:35 PM ET
Yankees @ OriolesOriole Park at Camden Yards · 1:35 PM ET
Cubs @ RedsGreat American Ball Park · 1:40 PM ET
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Nationals @ MetsCiti Field · 1:40 PM ET
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Jays @ RoyalsKauffman Stadium · 2:10 PM ET
Trey Yesavage
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proj K
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Michael Wacha
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proj K
Guardians @ TwinsTarget Field · 2:10 PM ET
Padres @ SoxRate Field · 2:10 PM ET
Brewers @ CardinalsBusch Stadium · 2:15 PM ET
Marlins @ RangersGlobe Life Field · 2:35 PM ET
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Angels @ RockiesCoors Field · 3:10 PM ET
Giants @ DodgersDodger Stadium · 4:10 PM ET
Trevor McDonald
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proj K
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Emmet Sheehan
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proj K
Phillies @ DiamondbacksChase Field · 4:10 PM ET
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Mariners @ AstrosDaikin Park · 7:10 PM ET
Sox @ RaysGeorge M. Steinbrenner Field · 7:35 PM ET
Want weather + park-adjusted lines?
The live engine layers game-day weather, air density, and Bayesian modeling on top of these baselines.
Open PitchProphet Engine →Proj K reflects each pitcher's baseline rate adjusted for the opposing lineup's strikeout rate vs. that hand (L3) and the ballpark's strikeout environment (L4). Game-day weather (L2) is applied in the live engine. For entertainment purposes only.